VISDB Viral Integration Site DataBase

VIS ID

TVIS10017740

Fusion event

HBV-HPS4 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

3106

Integrated sequence

GCGGCACACCAGGTAGGAGTGGGATCCTTCGGGCCAGGGTTCACTCCACCACACGGCAATCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAA| |CAGTACCAGCAGCGCCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGACAGCCTACTCCCATCTCTCCACCTCTAAGAGACAGTCATCCTCAGGCCAT

Chromosome

chr22

Cytoband

q12.1

Reference genome

Start

End

26877010/26481044 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-1180-3p ; hsa-mir-218-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-182-3p ; hsa-mir-5189-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-890 ; hsa-mir-8485 ; hsa-mir-6760-3p ; hsa-mir-603 ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-6732-3p ; hsa-mir-652-5p ; hsa-mir-4724-3p ; hsa-mir-6782-3p ; hsa-mir-3939

Nearest miRNA

hsa-mir-1286/Upstream/1025333; hsa-let-7a-3/Downstream/74168;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/46882, chr22-CpG: 72/Downstream/2448

Upstream sequence

ACCAACTTGGTCTCTTGGCACTGTCCTCTTTCCCAATACCTAAGGCTGGATGTACAACTGGCTGCAGGGTAAGCTCAGATCAAAAAGCCTCAAAAAAGTT

Downstream sequence

TCAAAGCCAACTCAGAAACTCCATGTGCACCCCAtcctcccctgtccccacgttctcttgatgaaagcatccctgcttgtgcgggcacacgaaagaaaac