Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017741
Fusion event
HBV-MYRIP integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
458
Integrated sequence
TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
Start
End
39949361/39907870 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/769604; hsa-let-7g/Downstream/4206342;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/97541, chr3-CpG: 88/Downstream/401496
Upstream sequence
tccctcattctttttttttttttttaacagtgcatagtattttagtgtgtagatttatttgtccagtcctctattgtggagcatttagtttgtttccagt
Downstream sequence
CCTGCAGCAAGATATCCAGACCTAAACTGGAATCACAGTTTATGCACTATGATTTTATATCATCAGGAACATTTACAAAGTGGTTTTAAAAATGACTGTT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.