VISDB Viral Integration Site DataBase

VIS ID

TVIS10017744

Fusion event

HBV-IGF2BP2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

core protein;X protein;

Start

1826

Integrated sequence

AGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATT

Chromosome

chr3

Cytoband

q27.2

Reference genome

Start

End

185415449/185697661 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-18a-5p ; hsa-let-7b-5p ; hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-877-5p ; hsa-mir-125a-3p ; hsa-mir-331-3p ; hsa-mir-129-5p ; hsa-mir-589-3p

Nearest miRNA

hsa-let-7g/Upstream/444389; hsa-mir-1248/Downstream/70186;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/110952, chr3-CpG: 288/Downstream/125599

Upstream sequence

TGTCCACCACCCCCTGCTAAACTCACCTCCATGCTGGCTTGTTTGACCTTCTGCACCTCAAACACCCTGTGCGGGGTCCCCTGCTGGTAGTTGATGTAGT

Downstream sequence

ACCTTTCTACTTTTGTTGCCTTTTCATTCACTTTTTTTTCCAAATTATAATCTGGAAAGATAAAAATCTTTTTAAAAATCATGAGATAcaaggcaggtgg