Fusion event
HBV-FIP1L1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein;Polymerase;
Integrated sequence
CGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGC| |ACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGC
End
54324863/53458696 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/745949; hsa-mir-1243/Downstream/7463923;
Nearest cancer related gene
Upstream sequence
TCAAAATGACTACATAAGACATCTTAAAATGCAAATCATTAATATCATCTAATAATTATAATTACCGTAATTCCACACAGATTTTCCTTAAAACTTACCA
Downstream sequence
ATGAGCGTCACAGAGCAAGTCGAGAAAAAGAAGAACGACATAGAGAAAGACGACACAGGGAGAAAGAGGAAACCAGACATAAGTCTTCTCGAAGGTTTGC
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.