VISDB Viral Integration Site DataBase

VIS ID

TVIS10017753

Fusion event

HBV-SFXN1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1775

Integrated sequence

AGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTG| |GGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAA

Chromosome

chr5

Cytoband

q35.2

Reference genome

Start

End

174909336/175482333 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-28-3p ; hsa-mir-421 ; hsa-mir-92b-3p ; hsa-mir-501-5p ; hsa-mir-31-5p ; hsa-mir-22-3p ; hsa-mir-4282 ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-150-3p ; hsa-mir-30e-5p ; hsa-mir-942-3p ; hsa-mir-4495 ; hsa-mir-1245b-3p ; hsa-mir-4802-3p ; hsa-mir-5683 ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-29b-2-5p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-563 ; hsa-mir-380-5p ; hsa-mir-3670 ; hsa-mir-3976 ; hsa-mir-3171 ; hsa-mir-4999-3p ; hsa-mir-587 ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-340-3p ; hsa-mir-3613-3p ; hsa-mir-3681-3p ; hsa-mir-4684-5p ; hsa-mir-548c-3p ; hsa-mir-6771-3p ; hsa-mir-6827-3p

Nearest miRNA

hsa-mir-10397/Upstream/730546; hsa-mir-1229/Downstream/885613;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/3271, chr5-CpG: 72/Downstream/175679

Upstream sequence

gtaccttggaacaaatggacttagcagatacatgcagaacattttatccaacaaccacagaatatgcattctattcaacagtgcatgcaactttttccaa

Downstream sequence

TAAAGGTCTTTGTACTAATTCCTCATAAAGCACATTCCCTGCTAACTTGTTTTCTACAAAATTTTGGAAAATTCTTTTTTTCTCCAGCAGTTAAGCATTT