VISDB Viral Integration Site DataBase

VIS ID

TVIS10017755

Fusion event

HBV-KCNQ3 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1648

Integrated sequence

CCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGT| |CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAG

Chromosome

chr8

Cytoband

q24.22

Reference genome

Start

End

133198728/132186481 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-629-3p ; hsa-mir-4713-5p ; hsa-mir-6867-5p ; hsa-mir-6752-3p ; hsa-mir-192-3p ; hsa-mir-6867-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4760-3p ; hsa-mir-223-5p ; hsa-mir-297 ; hsa-mir-511-3p ; hsa-mir-567

Nearest miRNA

hsa-mir-1204/Upstream/2178028; hsa-mir-10400/Downstream/860000;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/56912, chr8-CpG: 149/Downstream/293383

Upstream sequence

ttaaATAGAACACTTTATTACAGTGAGATGCTGCCTGGAGAGGGGATACCTGGAAGGGAAGGCCCTGTTTGTGGCAGAAGGGGATGGGAATACAGGTGCA

Downstream sequence

ACATTGCTGAAAGTCCAAAAGTCAAGACAACTTTTCACAAGTCATTAAGTATATGAATTAATTAATAATGTGTTCTACACACATAGGACTGATTTAAAAA