VISDB Viral Integration Site DataBase

VIS ID

TVIS10017761

Fusion event

HBV-MYO5B integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Region type

X protein;

Start

1805

Integrated sequence

CTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA

Chromosome

chr18

Cytoband

q21.1

Reference genome

Start

End

47472228/49945858 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-587 ; hsa-mir-1229-3p ; hsa-mir-1304-3p

Nearest miRNA

hsa-mir-1-2/Upstream/458436; hsa-mir-122/Downstream/180641;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/131272, chr18-CpG: 196/Downstream/247638

Upstream sequence

acttagactttgagcttaaaggaagtgacttggtgagacttagttggtttttgttggggCATGTCACAATAAGGGAGCAAGAAAACATTTTTGTAACCAG

Downstream sequence

GTGCTGAGAAAGCTCCATGGGGAAATAATGGGAGGCTGGAGGCAGGTTCACATTTTGAAGATGCCATTGTGATTCATGCCTGTCTGTCATGGCAAAGCAA