Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017762
Fusion event
HBV-TOMM7 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Region type
X protein;
Start
1775
Integrated sequence
AGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTG| |GGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAA
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
Start
End
22862349/22822730 (Hg38)
Location type
Exonic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1183/Upstream/1351584; hsa-mir-10399/Downstream/3127189;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/156928, chr7-CpG: 25/Downstream/51
Upstream sequence
ccactttgtcaatttctgcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaggcagctcctcagctgtcattttgatagggattgccctgagtctgagaatc
Downstream sequence
TGAAGAGCTGCTGTAGTCTCTGCTTGGCCTCTTTGCTCAGCTTCACCATGGCGACGGCCGTGTGGCGCAGGGAGGACCCCTTACAGCAACCACAGCGTCG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.