Fusion event
HBV-TMEM9 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
TTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGT| |CCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCT
End
201104510/201135382 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/2276229; hsa-mir-1182/Downstream/584126;
Upstream sequence
CTGGGAAATGATGGGTCAGATAAGGGAGCTACCAAGATTTCCCTaaacacccattgagtgcctactaagtgttggactctgccaggagatggagaaacaa
Downstream sequence
aatgaaaaagacacaatttttgtatttgagaagctcaaagaataaaggaggcagacaggaaaatgatcactaaaacacaGCATGATGTGCACCTTAACCA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.