VISDB Viral Integration Site DataBase

VIS ID

TVIS10017766

Fusion event

HBV-RYBP integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

370

Integrated sequence

CAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTAT| |CGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCG

Chromosome

chr3

Cytoband

p13

Reference genome

Start

End

72423905/72374754 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-93-5p ; hsa-mir-125b-5p ; hsa-mir-9-5p ; hsa-mir-129-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-580-3p ; hsa-mir-6857-3p ; hsa-mir-4790-3p ; hsa-mir-4251 ; hsa-mir-4499 ; hsa-mir-4463 ; hsa-mir-411-5p ; hsa-mir-151a-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-4696 ; hsa-mir-4645-3p ; hsa-mir-4777-3p ; hsa-mir-4999-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p

Nearest miRNA

hsa-let-7g/Upstream/832665; hsa-mir-12124/Downstream/2839722;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/589252, chr3-CpG: 116/Downstream/71948

Upstream sequence

GTCCACCACCCCCTGCTAAACTCACCTCCATGCTGGCTTGTTTGACCTTCTGCACCTCAAACACCCTGTGCGGGGTCCCCTGCTGGTAGTTGATGTAGTT

Downstream sequence

AGACAAAGAGCAGTGTCCAATATAAATTTCCCCCAAAACATTTAAGACCTGTGAATTTTTGACCAGTTCACAAAACCACCAACTGACACTTTAGCATGAA