Fusion event
HBV-FGG integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
CCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGT| |TGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGC
End
155526071/154604919 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/2068403; hsa-mir-1305/Downstream/4523883;
Upstream sequence
GTACTCCTCAGAACTGGAAAAGCACCAATTATATATAGATGAGACTGTGAATAGCAATATCCCAACTAACCTTCGTGTGCTTCGTTCAATCCTGGAAAAC
Downstream sequence
GTTGCTGTCCTTCTCCAATTGTGAGTCTGTTGAATGGGATTATCTTCATAGTGGTTTTCTTCATGGAATACCACCGGGTTTTCCAAGTGGCCCAAATAAT
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.