Fusion event
HBV-RBP7 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;
Integrated sequence
TCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTAAGGCAAGCTATTCTGTGTTGGGG| |TGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTAAGCTATGTCAATGTTAATATGGGCCTAAAA
End
10075876/10015818 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12136/Upstream/48360; hsa-mir-101-1/Downstream/2013340;
Upstream sequence
aaaaagcgacgtcgctatgaacgcttggccgccacaagccagttatccctgtggtaacttttctgacacctcctgcttaaaacccaaaaggtcagaagga
Downstream sequence
tcgtgaggccccgctttcacggtctgtattcgtactgaaaatcaagatcaagcgagcttttgcccttctgctccacgggaggtttctgtcctccctgagc
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.