Fusion event
HBV-RBP7 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
TCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGT| |ATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCT
End
10075892/10015834 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12136/Upstream/48376; hsa-mir-101-1/Downstream/2013324;
Upstream sequence
ATTCACAGCTCTTAATAATTGATCGTGGCTTTGATCCTGTGTCCACTGTCCTGCATGAACTGACCTTTCAGGCAATGGCATATGATCTACTACCAATTGA
Downstream sequence
GAATGATACATACAAGCAAGTATAACTTGAAGGGCATATAAAGGGCATATACAAACAGGATAGAATATGAGCATTTAATGATTTATATAGGCACCAGAAA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.