SERBP1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017776
Fusion event
HBV-SERBP1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
pre-S1/pre-S2/S;Polymerase;
Start
458
Integrated sequence
TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
End
67891967/67426284 (Hg38)
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-10a-5p ; hsa-mir-16-5p ; hsa-mir-93-3p ; hsa-mir-652-3p ; hsa-mir-625-5p ; hsa-mir-615-3p ; hsa-mir-505-3p ; hsa-mir-328-3p ; hsa-mir-374a-5p ; hsa-mir-30b-5p ; hsa-mir-15b-5p ; hsa-mir-100-5p ; hsa-mir-27a-3p ; hsa-mir-18a-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-8485 ; hsa-mir-548n ; hsa-mir-4699-3p ; hsa-mir-6509-5p ; hsa-mir-6732-3p ; hsa-mir-450b-5p ; hsa-mir-6750-3p ; hsa-mir-6512-5p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-4443 ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6134 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-219b-3p ; hsa-mir-1247-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-2054 ; hsa-mir-302f ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4799-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-651-5p ; hsa-mir-4715-3p ; hsa-mir-885-5p ; hsa-mir-22-3p ; hsa-mir-6802-5p ; hsa-mir-6800-5p ; hsa-mir-4645-3p ; hsa-mir-4790-3p ; hsa-mir-622 ; hsa-mir-3177-5p ; hsa-mir-5093 ; hsa-mir-875-3p ; hsa-mir-4308 ; hsa-mir-511-3p ; hsa-mir-504-5p ; hsa-mir-1257 ; hsa-mir-8060 ; hsa-mir-664a-3p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-548l ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-4501 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-513a-5p ; hsa-mir-4733-3p ; hsa-mir-370-5p ; hsa-mir-4764-3p ; hsa-mir-510-5p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4462 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-7845-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/797767; hsa-mir-11399/Downstream/757234;
Upstream sequence
TATAATACCTATCTCATTAGGGCACTGATAACTTAGCACCTGGGATAGGTTTGGTTCTCAGATTCCATAAGGCTGGGAGCAAGTAACTTAACCTGTGACT
Downstream sequence
GAATTATAGAATCTGCCTGATTCTCATAATTTCTGGTGTTTGTGAATTTTGGAATTTTGAGAGCAGTAGACAATAGATTTGCTGTATAATAAGCAGTAGC
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate