VISDB Viral Integration Site DataBase

VIS ID

TVIS10017784

Fusion event

HBV-PTMS integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1627

Integrated sequence

ACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGC| |CCGACAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAA

Chromosome

chr12

Cytoband

p13.31

Reference genome

Start

End

6879908/6770742 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-22-3p ; hsa-mir-193b-3p ; hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-296-3p ; hsa-mir-423-3p ; hsa-mir-1249-5p ; hsa-mir-1286 ; hsa-mir-135a-3p ; hsa-mir-363-5p ; hsa-mir-3675-5p ; hsa-mir-4269 ; hsa-mir-4436a ; hsa-mir-4514 ; hsa-mir-4692 ; hsa-mir-4742-5p ; hsa-mir-4772-5p ; hsa-mir-486-3p ; hsa-mir-5000-3p ; hsa-mir-5191 ; hsa-mir-5197-5p ; hsa-mir-5586-3p ; hsa-mir-6515-5p ; hsa-mir-6715b-5p ; hsa-mir-6721-5p ; hsa-mir-6745 ; hsa-mir-6757-5p ; hsa-mir-6797-5p ; hsa-mir-6804-5p ; hsa-mir-6808-5p ; hsa-mir-6819-5p ; hsa-mir-6880-5p ; hsa-mir-6893-5p ; hsa-mir-759 ; hsa-mir-7847-3p ; hsa-mir-940

Nearest miRNA

hsa-mir-3649/Upstream/5110362; hsa-let-7i/Downstream/192957;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/2985, chr12-CpG: 36/Downstream/2947

Upstream sequence

TGACATCAAGAAGGTGGTGAAGCAGGCGTCGGAGGGCCCCCTCAAGGGCATCCTGGGCTACACTGAGCACCAGGTGGTCTCCTCTGACTTCAACAGCGAC

Downstream sequence

ACCCACTCCTCCACCTTTGACGCTGGGGCTGGCATTGCCCTCAACGACCACTTTGTCAAGCTCATTTCCTGGTATGTGGCTGGGGCCAGAGACTGGCTCT