VISDB Viral Integration Site DataBase

VIS ID

TVIS10017787

Fusion event

HBV-RAB35 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1817

Integrated sequence

TGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTA

Chromosome

chr12

Cytoband

q24.23

Reference genome

Start

End

120539619/120101815 (Hg38)

Location type

Intronic

Fragile sites / regions

FRA12E ; FRA12C

Target gene

miRNAs that regulate target gene

hsa-mir-760 ; hsa-mir-193b-3p ; hsa-mir-30d-5p ; hsa-mir-96-5p

Nearest miRNA

hsa-let-7i/Upstream/388091; hsa-mir-3612/Downstream/53619;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/2668, chr12-CpG: 17/Downstream/1945

Upstream sequence

ATATGTATATATATTGACCAATGATTTTCCCATTTCCACATTTTAGCATTTGTACAAAACTTCTTTTAAAAAAAGACTCTAGTATCAACCTTTTCTGTAC

Downstream sequence

CAAGTAGTTTTATTTAATActtctagactagagtgtaaactcattgaccacagggataatgttttatacttcttCAAGCCACCTGTGGTATCTGTCACTA