VISDB Viral Integration Site DataBase

VIS ID

TVIS10017789

Fusion event

HBV-INTS6 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1761

Integrated sequence

ACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAA| |AGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACT

Chromosome

chr13

Cytoband

q14.3

Reference genome

Start

End

52001818/51427682 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-192-3p ; hsa-mir-4662a-5p ; hsa-mir-616-3p ; hsa-mir-4317 ; hsa-mir-95-5p

Nearest miRNA

hsa-mir-15a/Upstream/79043; hsa-mir-1267/Downstream/124907;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/175774, chr13-CpG: 186/Downstream/23873

Nearest cancer related gene

INTS6(TSG, No orient, 0)

Upstream sequence

TGTGTCAAGGTACTTATCTCTTCAAGCCTTCTGTGTACATATGATCTTTTTCTGGTATAAAAATTGGCAGGAACACTAATAAGTTACGAAACAAAAATAA

Downstream sequence

ATGTCACTAGATCTTAGAATGAGCTTAGGCAAATCTGTAATTTACCCGTAAGATAAAAGTTTTCTGAAACATGAGTATCGTGACCTTTCTTTGTAACAAC