Fusion event
HBV-RIN3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
CCGGAACAGTAAACCCTGTTCCGACTACTGCCTCTCCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAATATGGAGAGCACCACATCAGG| |ATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAAT
End
93154588/92688243 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1260a/Upstream/15421953; hsa-mir-1185-1/Downstream/1259983;
Upstream sequence
GAACTTTCATACAAATACTTAAAGGCAATAACAAAAAATGGAATTTCCTGAAAAACTCCCAATGGAATCCAAATCTGTTTCATCATCCTTCTGAAGTACA
Downstream sequence
TTCCTGTGAGGCCCTCCCGGGGCGCCTCCCCTCACCCCCAGGCGCACGTCTGGCCCCGCCTCTGGCTGCGCACTCCCGACCGCGACGTCCACGCAGCAGA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.