VISDB Viral Integration Site DataBase

VIS ID

TVIS10017794

Fusion event

HBV-SERPINA1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

216

Integrated sequence

CGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAATATGGAGAGCACCACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTT| |GTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAG

Chromosome

chr14

Cytoband

q32.13

Reference genome

Start

End

94847477/94381140 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1249-5p ; hsa-mir-1343-3p ; hsa-mir-3529-5p ; hsa-mir-379-5p ; hsa-mir-4419a ; hsa-mir-4451 ; hsa-mir-4510 ; hsa-mir-4650-3p ; hsa-mir-4690-5p ; hsa-mir-6081 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6783-3p ; hsa-mir-6797-5p ; hsa-mir-6832-5p

Nearest miRNA

hsa-mir-1260a/Upstream/432838; hsa-mir-1185-1/Downstream/756779;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/205829, chr14-CpG: 184/Downstream/387135

Upstream sequence

GTCGTCAGGGTGATCTCACCTTGGAGAGCTTCAGGGGTGCCTCCTCTGTGACCCCGGAGAGGTCAGCCCCATTGCTGAAGACCTTAGTGATGCCCAGTTG

Downstream sequence

CCTGGAGAGAGGGGAAGGTGGGCATCACCAGGGGTGAGTGAAGGTTTGGAAGAGTGTAGCAGAATAAAGAAACCATGAGTCCCCTCCCTGAGAAGCCCTG