Basic Information
VIS ID
TVIS10017795
Fusion event
HBV-DICER1-AS1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1795
Integrated sequence
TTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATT| |GGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT
Host Sequence
Chromosome
chr14
Cytoband
q32.13
Reference genome
GRCh37/hg19
Start
95629421/95163084 (Hg38)
End
95629421/95163084 (Hg38)
Location type
ncRNA
Target gene
DICER1-AS1
Nearest miRNA
hsa-mir-1260a/Upstream/25098; hsa-mir-1185-1/Downstream/4946335;
Nearest TSS
ENST00000550708/Upstream/5074; ENST00000439999/Downstream/14399;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/5201, chr14-CpG: 79/Downstream/156331
Upstream sequence
GCCTAAACGCTTCATCATAGGCACCTTCACGGTGGTCACCTGGTCCACGTGGAAGTCCTCTTCCTCGGTGTCCTTGACTTCAAAGGGTCTCTCCCATTTG
Downstream sequence
aagaaaaaaaaaatgttttaaaacacagttatctttctcttagaaaaatgggggtactcagtaaacagaattagaaaatcaccatttggcaatcatcaga
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate