LRRK1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017796
Fusion event
HBV-LRRK1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
core protein;X protein;
Start
1821
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAA
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
101585435/101045230 (Hg38)
End
101585435/101045230 (Hg38)
Location type
Intronic
Target gene
LRRK1
Nearest miRNA
hsa-mir-10393/Upstream/2260728; hsa-mir-1302-10/Downstream/915229;
Nearest TSS
ENST00000557528/Upstream/22890; ENST00000525395/Downstream/4226;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/36537, chr15-CpG: 40/Downstream/8012
Upstream sequence
TAATATAAAGTTATAGGAAATATGAGTTTTAAACTGTAACATTTTATATTGAACTTGTAGCCACCATGAACAAACCTTCTGAGGGGTGACTAAGGAGTCA
Downstream sequence
GCTGAAGGTAAAACCTTTATTGGGAAGGAGTGCAGCATCTGCACACCAGGGGCCGTCCTGTACCTGTCCAGTGCCTGCCCCCGCAGCCCCACAGGATGCA
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate