VISDB Viral Integration Site DataBase

VIS ID

TVIS10017797

Fusion event

HBV-ZNF688 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1833

Integrated sequence

GAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTG| |CCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCT

Chromosome

chr16

Cytoband

p11.2

Reference genome

Start

End

30581753/30570432 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-4263 ; hsa-mir-4659a-3p ; hsa-mir-4659b-3p ; hsa-mir-5680 ; hsa-mir-6875-3p

Nearest miRNA

hsa-mir-1225/Upstream/66431; hsa-mir-11401/Downstream/304834;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/219, chr16-CpG: 86/Downstream/983

Upstream sequence

ATGCTGCCTGTGGCTGACCAAGACCAATGCATAAGGCATTATGAAGGCAGCACAGTCCCCGAAAAGAAGACACCGAAGAGCCCTGTAGGGGTGCAGCCCA

Downstream sequence

TCTCCTGGGAAACCGGAATTAAGTTACACTTACAAACACTTTTGCACAGACTGTCTCAGGTTATAGAATGCTTTTCACTTAAGGCAGTGAGGGAAGTTCT