Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017804
Fusion event
HBV-EHBP1 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
X protein;
Start
1770
Integrated sequence
CTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTG| |TACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCC
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
Start
End
62929594/62702459 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1301/Upstream/496542; hsa-mir-10b/Downstream/1638288;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/196097, chr2-CpG: 61/Downstream/3001
Upstream sequence
GAGTTTATCAGATTTTTCTTAAGCGAAAATTAATCAATAGGGTATTTTGATAAGGGATAAAGAGAAGCAAAGAGGAGGGCACTGGTCAGTGGTGGGGAGA
Downstream sequence
TACCTGTTGGTTGGTAGGGGAAATGGGACCTTAAGAAAAGGGTAACTTCTAGCATGCCAAAAGTTCTCAGCTAATATATGACATAAGGAGTTGTCATGAG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.