DYSF _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017805
Fusion event
HBV-DYSF integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
pre-S1/pre-S2/S;Polymerase;
Start
377
Integrated sequence
CTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGA| |TGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCC
Host Sequence
Chromosome
chr2
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
71909756/71682626 (Hg38)
End
71909756/71682626 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA2S ; FRA2E
Target gene
DYSF
Nearest miRNA
hsa-mir-1285-2/Upstream/1429621; hsa-mir-10b/Downstream/3408186;
Nearest TSS
ENST00000437798/Upstream/71847; ENST00000498749/Downstream/460458;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/121859, chr2-CpG: 18/Downstream/103094
Upstream sequence
TTGTGAAATAGTCCTCTATCTACTTTTCTTCCTGCCTTCACTTTAAAAACTCAACTGTCTTAGAAAAATATATCCAAATTTACTATTTTTAGATGGACAT
Downstream sequence
atcctcttcatcCTGCTGCTGTTCCTGGCCATCTTCATCTACGCCTTCCCGGTGAGCAGGCCTGACGACACTGTGGTGGGGGAACTCTGGGTCTAATGGG
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
Curate