VISDB Viral Integration Site DataBase

VIS ID

TVIS10017808

Fusion event

HBV-CERS6 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1811

Integrated sequence

AGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCA| |CCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGA

Chromosome

chr2

Cytoband

q24.3

Reference genome

Start

End

169485620/168629110 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-6511b-3p ; hsa-mir-7159-3p ; hsa-mir-5088-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4762-5p ; hsa-mir-425-5p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-551b-5p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-128-1/Upstream/46092; hsa-mir-10b/Downstream/6538523;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/171998, chr2-CpG: 22/Downstream/261099

Upstream sequence

GGCTGCCACTCCATTACATACTCGCTGCAACACACAGCATCCCAGTGAAGCACAGACAGTAAAGCAGTGTTAACAGCAAGCATTTGTCCAAATCGCTGCT

Downstream sequence

AATGATGGAGGCATCAGTATTCCTATAATAGAATCTATGTGTTATGAAAACTGGGTCATTTTAGTGATTAAATAAAATGTAGATACATAAATGATGGTAG