Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
pre-S1/pre-S2/S;Polymerase;
Integrated sequence
TGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAG| |GTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCC
End
216240117/215375394 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1617235; hsa-mir-1244-1/Downstream/2525119;
Upstream sequence
gggggggaggggggggggggaggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggagggggggg
Downstream sequence
TGAAAGAAAACAAAATTAAGTCTCTAAGAAGGCAAATAACCAAGAAAATTACTCCCACACTTTTCTCCCGAGCCGTTCTAAACACACTTAAAAGAATCTG
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.