Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;
Integrated sequence
TCACCTCACCATACAGCACTAAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCA| |GGGAATTAGTAGTAAGCTATGTCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGT
End
216240188/215375465 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1617306; hsa-mir-1244-1/Downstream/2525048;
Upstream sequence
tcccttcccttcccttcccttcccttcccttcccttcccttcccttccctttcgcttcccctccccctggccctcccctccccccctcccctccccctcc
Downstream sequence
GCCGTTCTAAACACACTTAAAAGAATCTGAGAATACTGTAAACCGGAAACAAGATTCTCTGGAATCTATAATACAAAAATATACGCCTCACATTTGTTTT
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.