Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;X protein;
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGA
End
216280194/215415471 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1657312; hsa-mir-1244-1/Downstream/2485042;
Upstream sequence
CCACCTGGGTCCTAGGGTACACTGGCAGAGAGCACCCTGTAGGCTGCTCAGTGTCTTGTCTGGTTCTGTGGGGAAAGGGCTACCAGACTTTCTAAAGCTC
Downstream sequence
CTTAGACAAATAGCAAAGGTAATAATTAAAGACCTAGTTTTATTTCTCATCAGTCTAAGCAGTCTATCAGTTTGGAAAAAACATCAAGTTTTATTTTTAT
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.