VISDB Viral Integration Site DataBase

VIS ID

TVIS10017814

Fusion event

HBV-IFNAR1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

Polymerase;

Start

2588

Integrated sequence

GCTTTATTCTTCTACTGTACCTGTCTTTAATCCTGACTGGCAAACTCCCTCTTTTCCTCACATTCATTTGAAAGAGGATATTATCAATAGATGTCAACAA| |TATGTAGGCCCTCTTACAGTTAACGAAAAAAGGAGATTAAAATTGATTATGCCTGCTAGGTTCTATCCTAACCATACCAAATATTTGCCTTTAGATAAAG

Chromosome

chr21

Cytoband

q22.11

Reference genome

Start

End

34713291/33340985 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-6083 ; hsa-mir-3121-3p ; hsa-mir-3976 ; hsa-mir-1273f ; hsa-mir-6890-5p ; hsa-mir-410-3p ; hsa-mir-6516-5p ; hsa-mir-1273e ; hsa-mir-455-3p ; hsa-mir-6820-5p ; hsa-mir-381-5p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4537 ; hsa-mir-219b-3p ; hsa-mir-1247-3p ; hsa-mir-3919 ; hsa-mir-3123 ; hsa-mir-302f ; hsa-mir-7704 ; hsa-mir-615-5p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-3190-5p ; hsa-mir-1277-5p ; hsa-mir-618 ; hsa-mir-498 ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-1266-3p ; hsa-mir-660-3p ; hsa-mir-6890-3p ; hsa-mir-1306-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4755-3p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-483-5p ; hsa-mir-29a-3p

Nearest miRNA

hsa-let-7c/Upstream/2965607; hsa-mir-3197/Downstream/209677;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/15540, chr21-CpG: 108/Downstream/62146

Upstream sequence

AAACAAGAGTTATTAAGAGTTAAGAAATAACTCTTATACCAGTAAATAGAAAGTATTTGACACTTACATTTATACATTTGCTCACTCATTCATTTGTTTT

Downstream sequence

TTTTACTTTAAAGAACTGGGATGGATAATTGGATAAAATTGTCTGGGTGTCAGAATATTACTAGTACCAAATGCAACTTTTCTTCACTCAAGCTGAATGT