VISDB Viral Integration Site DataBase

VIS ID

TVIS10017817

Fusion event

HBV-TRAK1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1762

Integrated sequence

CTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAA| |GGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTG

Chromosome

chr3

Cytoband

p22.1

Reference genome

Start

End

42252915/42211423 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-324-3p ; hsa-mir-93-5p ; hsa-mir-374b-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-711

Nearest miRNA

hsa-mir-12127/Upstream/3073157; hsa-let-7g/Downstream/1902789;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/8544, chr3-CpG: 33/Downstream/52029

Upstream sequence

CCCTTTTAAGATTTCTCATTGTCCATACACTCAGAAATGAGAAGAGGGATTTTCTCATTCTGATCCTAAATCTATCACTGAAATGATGACTTCACTTGCA

Downstream sequence

TTTTATTTGTTATCTACACACTCGAAAAAGAGAAACCAGCTGCGGTACTGTCCCATTTTTGTCATCAGCACCAGTGTCCGTCAGGAAGGCAGGTGGTGGT