VISDB Viral Integration Site DataBase

VIS ID

TVIS10017818

Fusion event

HBV-EPHA6 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1790

Integrated sequence

CGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCAT| |AAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG

Chromosome

chr3

Cytoband

q11.2

Reference genome

Start

End

97280243/97561399 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-18a-3p ; hsa-mir-216b-5p ; hsa-mir-3675-3p ; hsa-mir-4290 ; hsa-mir-4667-3p ; hsa-mir-4691-5p ; hsa-mir-4762-5p ; hsa-mir-5193 ; hsa-mir-519d-5p ; hsa-mir-520f-5p ; hsa-mir-6779-3p ; hsa-mir-6792-3p

Nearest miRNA

hsa-let-7g/Upstream/1201360; hsa-mir-12124/Downstream/2402915;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/746618, chr3-CpG: 38/Downstream/202897

Upstream sequence

GGTTTCCATGTGCTACTCACATGTTGCTTTTGGCATTCCTCAGGAAAATACAACTGTATATTACTTAGTCTTAGATGTGCAAGAATCGGACTGTTCGGTC

Downstream sequence

gcagccttattactgatagggataaagttttagtggtctggatagatcaaaccacaacattcccttaagccaaagtctgatggagagcaaggccctctct