Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017819
Fusion event
HBV-CHCHD6 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Region type
Polymerase;
Start
1162
Integrated sequence
TATGCATGTATACAAGCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGAACCTTTACCCCGTTGCTCGGCAAC| |GGTCAGGTCTTTGCCAAGTATTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCC
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
End
126577144/126858301 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/1067749; hsa-mir-12124/Downstream/716965;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/153535, chr3-CpG: 27/Downstream/91115
Upstream sequence
GCCGTGCTTCAAAAGTGACCACGGACGCAGGTTCACGATGGGAGAAAGGATCGGCGCAATTAAGCAAGAGTCCGAAGAACCCCCCACAAAAAAGAACCGG
Downstream sequence
gggggcgggggggaggggtgggtaaggcttcctttcatgaccttggtgttagttacaggtgtgttcagttgctgagagttcatctggctgtgctctcagg
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.