VISDB Viral Integration Site DataBase

VIS ID

TVIS10017820

Fusion event

HBV-CPNE4 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1634

Integrated sequence

TTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAG| |GTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGG

Chromosome

chr3

Cytoband

q22.1

Reference genome

Start

End

131423230/131704386 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-122-5p

Nearest miRNA

hsa-let-7g/Upstream/2432143; hsa-mir-1224/Downstream/281469;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/177209, chr3-CpG: 25/Downstream/330650

Upstream sequence

AACTTGGACTCAACAATAAGTCACTGAAAAATATATTTTCTTTATGTGCTTGTTACTTACACACCTAAAGcactcattgaaaaagttgcatggtattgca

Downstream sequence

gctcttttgtctcagtagtgagggctgacactgggtgtttgttcaatatgggtgcctgacttgtcccagtgaaatgaagctccagtttctcccagtggtg