VISDB Viral Integration Site DataBase

VIS ID

TVIS10017821

Fusion event

HBV-TF integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

366

Integrated sequence

CTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGG| |TTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTG

Chromosome

chr3

Cytoband

q22.1

Reference genome

Start

End

133479942/133761098 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-19a-3p

Nearest miRNA

hsa-let-7g/Upstream/1775167; hsa-mir-1224/Downstream/606706;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/14522, chr3-CpG: 35/Downstream/22619

Upstream sequence

CCGGAAAACACGCACAGTGGTGCAGCCTAGTGTTGGTGCTGCTGCTGGGCCAGTGGTTCCTCCATGTCCGGGGAGGATCAGACACTTCAAGGTCTAGGCT

Downstream sequence

AGTGACCAGTGCCCTCGGTTATTGCAGTAATCATGTTCATGAGTAGACACACAGGACTTCCAAAGGGAGTCATCATCTCGCATAGAAACATCATTACTGG