Fusion event
HBV-ARMC8 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
core protein;X protein;
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAA
End
137948268/138229426 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/3791520; hsa-mir-1224/Downstream/13336450;
Upstream sequence
ATTTAAGTTTGGCTCTAAACCAAACGAGATTTCCTTAGCACAGTGCTTTGAAATCTTTTTCATATAATAGCACCCATAGAAAAAGTTGCTCAGTGCTGAT
Downstream sequence
cttatgctattacaaaacagtgctgcaaaaaataccttgtatatgaggcattttataagaaataaaattttggggtcaaagaatatatgtatttgtaatt
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.