VISDB Viral Integration Site DataBase

VIS ID

TVIS10017823

Fusion event

HBV-NLGN1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1818

Integrated sequence

GTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT

Chromosome

chr3

Cytoband

q26.31

Reference genome

Start

End

173309656/173591866 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-1251-3p ; hsa-mir-31-3p ; hsa-mir-4705 ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p

Nearest miRNA

hsa-let-7g/Upstream/2485107; hsa-mir-1224/Downstream/1777674;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/193881, chr3-CpG: 28/Downstream/785339

Upstream sequence

ATGTGCTTCTGTAATGGGCAGTGTTCATCAGAGGGTTTGCTCCCATTGCTCAAGAGTAGAGATGCTTCCTCCCAGGGCTGACTTCCCATAGGTATTTTCC

Downstream sequence

TGGAAGCAATGACTTGTGACCCAAAGGTGGCCCCTTCCAGACAAAATCATCAACTTAATATCAAGGGAAGTAATCAGCTCTACCAGGCTGTCTCTTCTGA