VISDB Viral Integration Site DataBase

VIS ID

TVIS10017844

Fusion event

HBV-FN1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

279

Integrated sequence

TAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCT| |AGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATG

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216251414/215386691 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1628532; hsa-mir-1244-1/Downstream/2513822;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/74282, chr2-CpG: 43/Downstream/48853

Upstream sequence

AGAGCTATTTCGCAACTGACAAACAGTATATTCATATGTCTGGTAATGGTTATCTATTATTGGCTCTGGCTTTGTCTTCTCTCTGGGtctgggcctcagt

Downstream sequence

TTGATTGTTGGCCAATCAATAAGGGACTTTCCTCTCTGCCATTAAGAGCAACGATGCTGACCACATACTCTGTGCCTGGAGTGAGGTTGGTGAGGGTGAT