Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGA| |CAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACT
End
216252677/215387954 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1629795; hsa-mir-1244-1/Downstream/2512559;
Upstream sequence
TGCTTTTTCAAGTTGCAAGATGCTTGAAAATTTTGCTTTCTGCAGATATTTTGTGGAAATAAACTCTGCCTTGTAAATATTCATCACAAGTTGCTATTCA
Downstream sequence
AAGATCTTCTTAGAAAATGTTTTTTAAAAGGACAGACAACAAATTTCTTAATTTGTTAGTGACTGAAAGTCTAGGTGATTGTTGAGTAAGGTATCTTTTA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.