VISDB Viral Integration Site DataBase

VIS ID

TVIS10017854

Fusion event

HBV-TCN2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

335

Integrated sequence

ATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTGCAGTCCCCAACCTCCAATCACT| |CACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTT

Chromosome

chr22

Cytoband

q12.2

Reference genome

Start

End

31019122/30623135 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-6873-5p ; hsa-mir-3149 ; hsa-mir-4776-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-6832-5p ; hsa-mir-4653-3p ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4735-5p ; hsa-mir-6514-5p ; hsa-mir-590-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-6778-3p ; hsa-mir-186-3p

Nearest miRNA

hsa-mir-1286/Upstream/616022; hsa-let-7a-3/Downstream/108422;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/30738, chr22-CpG: 21/Downstream/12236

Upstream sequence

GGGAGTTCTGGCAGCTTCTCCGAGACCCCAACACCCCACTGTTGCAAGGTGAGTCATGGCCTGACACTCTGGATGTGTCCCCTACCCCAAGCTTACTCAG

Downstream sequence

CCAAGAGGCTTCATCAACTCACCCCAGCTTTCCCTAGCACCCTCCTGGGCCACACCTTCACAAAATCACTGATGCTCAAAGTTGGATATAATATATTGAA