VISDB Viral Integration Site DataBase

VIS ID

TVIS10017855

Fusion event

HBV-XRN1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1777

Integrated sequence

CAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGG| |AGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGC

Chromosome

chr3

Cytoband

q23

Reference genome

Start

End

142089887/142371045 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-10a-5p ; hsa-let-7b-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-4747-3p ; hsa-mir-1295b-3p ; hsa-mir-6507-5p ; hsa-mir-1277-5p ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p

Nearest miRNA

hsa-let-7g/Upstream/7933139; hsa-mir-1224/Downstream/9194831;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/145367, chr3-CpG: 71/Downstream/76315

Upstream sequence

TCCTTCAATAATTGCTAATATAATCATAATGTAGTAAGACAATATGGGAACACATACAAGCAAACAAAAGGACTTGTTCGTTTATTATTAGTTATATCAG

Downstream sequence

ggattgtttgagtccagggaaccaaggctaaagtgagccacatttgagccactgcattcgggcaagagagtaagaacctgtctcaaaaaaaaaaaaaaaa