VISDB Viral Integration Site DataBase

VIS ID

TVIS10017856

Fusion event

HBV-GRID2 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1832

Integrated sequence

GGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCT| |GCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGC

Chromosome

chr4

Cytoband

q22.2

Reference genome

Start

End

94270265/93349114 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-448

Nearest miRNA

hsa-mir-12113/Upstream/6048531; hsa-mir-1243/Downstream/5648273;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/1043258, chr4-CpG: 112/Downstream/479230

Upstream sequence

TTTGTTTTTCAGCCTACCATGAGAATAAGAGAAAGAAAATGAAGATCAAAAGCTTATTCATCTGTTTTTCTTTTTCGTTGGTGTAAAGCCAACACCCTGT

Downstream sequence

TCTTCATATATACAGGCACATTTTCACATCATGTGAATATTGTATGAAGATGTCACAAATTATATGTTCACATGTACATATATTATCATTTTCACATGAA