VISDB Viral Integration Site DataBase

VIS ID

TVIS10017858

Fusion event

HBV-FGB integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

460

Integrated sequence

TCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGT| |ATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCT

Chromosome

chr4

Cytoband

q31.3

Reference genome

Start

End

155488866/154567714 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-409-3p ; hsa-mir-29c-3p ; hsa-mir-144-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-5096 ; hsa-mir-5587-5p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-197-3p ; hsa-mir-6832-5p ; hsa-mir-6801-5p ; hsa-mir-193b-5p ; hsa-mir-1279 ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-6890-5p

Nearest miRNA

hsa-mir-12113/Upstream/2031198; hsa-mir-1305/Downstream/4561088;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/17184, chr4-CpG: 39/Downstream/59118

Upstream sequence

ACTTGCTATTCTGAGTACTGTGATTTTCATTTACTTCTAGCAATACAGGATTACAATTAAGAGGACAAGATCTGAAAATCTCACAAACTATAAAATAATA

Downstream sequence

CTGAGAAGCAAAATACAAAAGTTAGAATCTGATGTCTCAGCTCAAATGGAATATTGTCGCACCCCATGCACTGTCAGTTGCAATATTCCTGTGGTGTCTG