Fusion event
HBV-FGB integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein;Polymerase;
Integrated sequence
CGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCT| |GTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCGACAGGTCTTGCCCAAGGTCTTACA
End
155490477/154569325 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/2032809; hsa-mir-1305/Downstream/4559477;
Upstream sequence
CAGCAAATGAGGAGCCGGAGTATCACACAACACAGGAAGCTTTATTCATCCGCTGCTGGTCCAAAGAGTGGGTCGCAGGGTCACTCACTTTAATATGCTG
Downstream sequence
AAATAAAATCATTCTATTTGAAATGGGATTTTTTTTAATTAAAAAACATTCATTGTTGGAAGCCTGTTTTAGGCAGTTAAGAGGAGTTTCCTGACAAAAA
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.