VISDB Viral Integration Site DataBase

VIS ID

TVIS10017862

Fusion event

HBV-ARID1B integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;X protein;

Start

1833

Integrated sequence

GAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTG| |CCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCT

Chromosome

chr6

Cytoband

q25.3

Reference genome

Start

End

157206236/156885102 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-92b-3p ; hsa-mir-324-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-578 ; hsa-mir-643 ; hsa-mir-138-2-3p ; hsa-mir-5692a ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-mir-3143 ; hsa-let-7a-3p ; hsa-mir-656-3p ; hsa-mir-144-3p ; hsa-mir-602 ; hsa-mir-543

Nearest miRNA

hsa-mir-10398/Upstream/105371; hsa-mir-1913/Downstream/644030;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/164898, chr6-CpG: 134/Downstream/135824

Upstream sequence

AGAGGCCTGGGGAGGCGGCTGTGGCCTCGTCGCCTTCCAAAGCGAACGGACAGGTAAATTCTACCTGTGGTTGTGGTCATTTATTTCGTGTCTTTCTCTC

Downstream sequence

TAATATAGCTAAAATAAAGTAAAATTGGAATATGATCTAATTTCAGAACTAAAATATTTTAGCCCAGTTATCCTTATATGTCACTGGATTTTGGAGGGTT