VISDB Viral Integration Site DataBase

VIS ID

TVIS10017866

Fusion event

HBV-LEMD3 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1800

Integrated sequence

GCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCT| |GTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC

Chromosome

chr12

Cytoband

q14.3

Reference genome

Start

End

65636246/65242466 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-22-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p

Nearest miRNA

hsa-let-7i/Upstream/619861; hsa-mir-1178/Downstream/781154;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/71850, chr12-CpG: 88/Downstream/36140

Upstream sequence

AAGGGGGATTTCCTCTAAACTAAATATAAGAAGAATAGAGAGAATCATCTCACCATCCCTGGTCACTCTTGAATTTGTAGGCAGCTGCAAGAATGTGGCA

Downstream sequence

CAAGGAGCCTCCCGCTTTGAAATCTAGGAAACATTTGATCTACAAAATCAAGATACGGAAAAAGCATGTCAAGGTTCCACTGTAAATTCTCTCATCACTT