DNAJC7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017867
Fusion event
HBV-DNAJC7 integration
Validated
No
Detection method
TS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26867494
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
DQ089769.1
Region type
X protein;
Start
1737
Integrated sequence
TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTATTTAAAGACTGGGAGG| |AGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTA
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
40133968/41981950 (Hg38)
End
40133968/41981950 (Hg38)
Location type
Exonic
Target gene
DNAJC7
miRNAs that regulate target gene
hsa-mir-181a-5p ; hsa-mir-877-3p
Nearest miRNA
hsa-mir-1180/Upstream/464733; hsa-mir-10226/Downstream/512823;
Nearest TSS
ENST00000595228/Upstream/10341; ENST00000587028/Downstream/371;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/13497, chr17-CpG: 67/Downstream/35031
Upstream sequence
TACAGTTCATCTTTCACAGCTTTCTGATCATCGTCTTCCTCCATGTCTGGCTCCTCTGCTTCTTCCAGGTCCTCGAGATCCTGGGATACAGGAAAAGGGG
Downstream sequence
CCTTGAACTTCTTCTCCTCCTCCTTCTGAACCTCAGCACTGGCTCCACTATGCCGATCTAAAGTGGGGAGTAAAAGAACAACTCAGTGGAAATCAAAGTT
Reference
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.
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