VISDB Viral Integration Site DataBase

VIS ID

TVIS10017871

Fusion event

HBV-PSAP integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

core protein;

Start

1929

Integrated sequence

TCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGG| |AGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGTGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAG

Chromosome

chr10

Cytoband

q22.1

Reference genome

Start

End

73576961/71817204 (Hg38)

Location type

3UTR

Target gene

miRNAs that regulate target gene

hsa-mir-19a-3p ; hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-mir-19b-3p ; hsa-mir-615-3p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-mir-149-5p ; hsa-mir-191-5p ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-24-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-377-3p ; hsa-mir-210-3p ; hsa-mir-1197 ; hsa-mir-1233-3p ; hsa-mir-1275 ; hsa-mir-1343-5p ; hsa-mir-3689d ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4525 ; hsa-mir-4665-5p ; hsa-mir-4723-5p ; hsa-mir-5010-5p ; hsa-mir-5680 ; hsa-mir-5698 ; hsa-mir-6134 ; hsa-mir-625-5p ; hsa-mir-6799-5p ; hsa-mir-6825-5p ; hsa-mir-6827-5p ; hsa-mir-6851-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-92a-2-5p ; hsa-mir-939-5p

Nearest miRNA

hsa-mir-1265/Upstream/26404; hsa-mir-107/Downstream/903825;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/43469, chr10-CpG: 41/Downstream/33700

Upstream sequence

GCACAAGCCTTGAGGcagcatttcttaactggtcatagatgcttttgaaaccctgataaaatgtgggaggatctccctgggaaaatgaacacacgtgcac

Downstream sequence

attcacaaagttacacatgcaacttTGAAAGAACACAGTACAGAGTGAAGATGCTTGCTTTAAAGAAAATACCTAGAATTCGATCTCACTGAGATGGTTG