Fusion event
HBV-LINC00486 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein;Polymerase;
Integrated sequence
TCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGACTCTACCGTCCCCTTCTTCGTCTGCCGTTCCGGCCGA| |CCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACC
End
33141531/32916464 (Hg38)
Nearest miRNA
hsa-mir-1301/Upstream/281133; hsa-mir-10b/Downstream/502052;
Upstream sequence
TACACAGTGATGGTATAATCAACTCCAGGTTTAAGGCCGCTGATGGTAGCTGTAGACTTGCTCCCAGGCACAGTGAACTCCTGGACAGGGCTATTTCCTC
Downstream sequence
ggggggggaggggggggggggaggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggaggggggg
Chiu, Y. T., et al. Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. J Hepatol ,2016,64(6): 1256-1264.