VISDB Viral Integration Site DataBase

VIS ID

TVIS10017885

Fusion event

HBV-IKZF1 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

X protein;

Start

1813

Integrated sequence

ACTGTGTATTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGATTAAAGGTCTTTGTACTGGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCCACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACC

Chromosome

chr7

Cytoband

p12.2

Reference genome

Start

End

50358030/50318434 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-1183/Upstream/5436634; hsa-mir-10399/Downstream/6637351;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/13511, chr7-CpG: 79/Downstream/81434

Nearest cancer related gene

IKZF1(OG, No orient, 0)

Upstream sequence

GGCGAGACAGGAAGCGTGATTTGCTGGTGTGATCAGTCAGTTGCACCTCCCCGCCCTGCAGGACTCAGTGTGTCCGGCAGACAGTCCTACCTGGTTGGCT

Downstream sequence

GGCTGAGGCAAGGGCCCAGAAAGATTGAGGGACAAAGACAGGAGCGCCCGCATTGCCCATCTGCCAGGCTGGAGGTGTATTCATTATTGATGGAGGTAGT