VISDB Viral Integration Site DataBase

VIS ID

TVIS10017886

Fusion event

HBV-PARP10 integration

Validated

No

Detection method

TS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Region type

pre-S1/pre-S2/S;Polymerase;

Start

313

Integrated sequence

CTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTTG| |CAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCC

Chromosome

chr8

Cytoband

q24.3

Reference genome

Start

End

145057608/143983440 (Hg38)

Location type

stopgain

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-421 ; hsa-mir-132-3p

Nearest miRNA

hsa-mir-1204/Upstream/38161; hsa-mir-10400/Downstream/73881;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/5303, chr8-CpG: 126/Downstream/6311

Upstream sequence

ttgttacactgaaagatgaaggaggcagatgagagaaggaccctggggagtctccaaacctccgcacaagtgtttacatcagatgcttttgtgcagatga

Downstream sequence

CTCAAAGGCCGAGTGCACCACCAGCTGGGCCTTGCCATCAGTCCCCCCATCTGGGGGCTCTTCTGCCTCCAACGGGGGCTGCTCCAGCAGGGAGAGGGTT